Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus

Abstract Efficacious therapeutics for Ebola virus disease are in great demand. Ebola virus infections mediated by mucosal exposure, and aerosolization in particular, present a novel challenge due to nontypical massive early infection of respiratory lymphoid tissues. We performed a randomized and bli...

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Bibliographic Details
Main Authors: Travis K. Warren, Christopher D. Kane, Jay Wells, Kelly S. Stuthman, Sean A. Van Tongeren, Nicole L. Garza, Ginger Donnelly, Jesse Steffens, Laura Gomba, Jessica M. Weidner, Sarah Norris, Xiankun Zeng, Roy Bannister, Tomas Cihlar, Sina Bavari, Danielle P. Porter, Patrick L. Iversen
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98971-0