miR-146a targets Fos expression in human cardiac cells

miR-146a targets Fos expression in human cardiac cells

miR-146a is a microRNA whose transcript levels are induced in the heart upon activation of NF-κB, a transcription factor induced by pro-inflammatory molecules (such as TNF-α) that is strongly related to the pathogenesis of cardiac disorders. The main goal of this study consisted of studying new role...

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Bibliographic Details
Main Authors: Xavier Palomer, Eva Capdevila-Busquets, Gaia Botteri, Mercy M. Davidson, Cristina Rodríguez, José Martínez-González, Francisco Vidal, Emma Barroso, Tung O. Chan, Arthur M. Feldman, Manuel Vázquez-Carrera
Format: Article
Language:English
Published: The Company of Biologists 2015-09-01
Series:Disease Models & Mechanisms
Subjects:
Fos
Cardiac remodeling
Inflammation
miR-146a
Matrix metalloproteinase-9
Online Access:http://dmm.biologists.org/content/8/9/1081

Internet

http://dmm.biologists.org/content/8/9/1081

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