Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad

Canine rabies, and thus human exposure to rabies, can be controlled through mass vaccination of the animal reservoir if dog owners are willing to cooperate. Inaccessible, ownerless dogs, however, reduce the vaccination coverage achieved in parenteral campaigns. This study aimed to estimate the vacci...

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Main Authors: Kayali U., Mindekem R., Yémadji N., Vounatsou P., Kaninga Y., Ndoutamia A.G., Zinsstag J.
Format: Article
Language:English
Published: The World Health Organization 2003-01-01
Series:Bulletin of the World Health Organization
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862003001000009
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author Kayali U.
Mindekem R.
Yémadji N.
Vounatsou P.
Kaninga Y.
Ndoutamia A.G.
Zinsstag J.
author_facet Kayali U.
Mindekem R.
Yémadji N.
Vounatsou P.
Kaninga Y.
Ndoutamia A.G.
Zinsstag J.
author_sort Kayali U.
collection DOAJ
description Canine rabies, and thus human exposure to rabies, can be controlled through mass vaccination of the animal reservoir if dog owners are willing to cooperate. Inaccessible, ownerless dogs, however, reduce the vaccination coverage achieved in parenteral campaigns. This study aimed to estimate the vaccination coverage in dogs in three study zones of N'Djaména, Chad, after a pilot free parenteral mass vaccination campaign against rabies. We used a capture-mark-recapture approach for population estimates, with a Bayesian, Markov chain, Monte Carlo method to estimate the total number of owned dogs, and the ratio of ownerless to owned dogs to calculate vaccination coverage.When we took into account ownerless dogs, the vaccination coverage in the dog populations was 87% (95% confidence interval (CI), 84-89%) in study zone I, 71% (95% CI, 64-76%) in zone II, and 64% (95% CI, 58-71%) in zone III. The proportions of ownerless dogs to owned dogs were 1.1% (95% CI, 0-3.1%), 7.6% (95% CI, 0.7-16.5%), and 10.6%(95% CI, 1.6-19.1%) in the three study zones, respectively. Vaccination coverage in the three populations of owned dogs was 88% (95% CI, 840-92%) in zone I, 76% (95% CI, 71-81%) in zone II, and 70% (95% CI, 66-76%) in zone III. Participation of dog owners in the free campaign was high, and the number of inaccessible ownerless dogs was low. High levels of vaccination coverage could be achieved with parenteral mass vaccination. Regular parenteral vaccination campaigns to cover all of N'Djaména should be considered as an ethical way of preventing human rabies when post-exposure treatment is of limited availability and high in cost.
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spelling doaj.art-8b26100f42b7493ca7fd8f44f3ec9e282024-03-02T04:41:31ZengThe World Health OrganizationBulletin of the World Health Organization0042-96862003-01-018110739744Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, ChadKayali U.Mindekem R.Yémadji N.Vounatsou P.Kaninga Y.Ndoutamia A.G.Zinsstag J.Canine rabies, and thus human exposure to rabies, can be controlled through mass vaccination of the animal reservoir if dog owners are willing to cooperate. Inaccessible, ownerless dogs, however, reduce the vaccination coverage achieved in parenteral campaigns. This study aimed to estimate the vaccination coverage in dogs in three study zones of N'Djaména, Chad, after a pilot free parenteral mass vaccination campaign against rabies. We used a capture-mark-recapture approach for population estimates, with a Bayesian, Markov chain, Monte Carlo method to estimate the total number of owned dogs, and the ratio of ownerless to owned dogs to calculate vaccination coverage.When we took into account ownerless dogs, the vaccination coverage in the dog populations was 87% (95% confidence interval (CI), 84-89%) in study zone I, 71% (95% CI, 64-76%) in zone II, and 64% (95% CI, 58-71%) in zone III. The proportions of ownerless dogs to owned dogs were 1.1% (95% CI, 0-3.1%), 7.6% (95% CI, 0.7-16.5%), and 10.6%(95% CI, 1.6-19.1%) in the three study zones, respectively. Vaccination coverage in the three populations of owned dogs was 88% (95% CI, 840-92%) in zone I, 76% (95% CI, 71-81%) in zone II, and 70% (95% CI, 66-76%) in zone III. Participation of dog owners in the free campaign was high, and the number of inaccessible ownerless dogs was low. High levels of vaccination coverage could be achieved with parenteral mass vaccination. Regular parenteral vaccination campaigns to cover all of N'Djaména should be considered as an ethical way of preventing human rabies when post-exposure treatment is of limited availability and high in cost.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862003001000009Rabies vaccines/administration and dosageDogs/immunologyVaccination/methodsMass immunizationPilot projectsBayes theoremChad
spellingShingle Kayali U.
Mindekem R.
Yémadji N.
Vounatsou P.
Kaninga Y.
Ndoutamia A.G.
Zinsstag J.
Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad
Bulletin of the World Health Organization
Rabies vaccines/administration and dosage
Dogs/immunology
Vaccination/methods
Mass immunization
Pilot projects
Bayes theorem
Chad
title Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad
title_full Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad
title_fullStr Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad
title_full_unstemmed Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad
title_short Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad
title_sort coverage of pilot parenteral vaccination campaign against canine rabies in n djamena chad
topic Rabies vaccines/administration and dosage
Dogs/immunology
Vaccination/methods
Mass immunization
Pilot projects
Bayes theorem
Chad
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862003001000009
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