SampleQC: robust multivariate, multi-cell type, multi-sample quality control for single-cell data
Abstract Quality control (QC) is a critical component of single-cell RNA-seq (scRNA-seq) processing pipelines. Current approaches to QC implicitly assume that datasets are comprised of one cell type, potentially resulting in biased exclusion of rare cell types. We introduce SampleQC, which robustly...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-023-02859-3 |