SampleQC: robust multivariate, multi-cell type, multi-sample quality control for single-cell data

Abstract Quality control (QC) is a critical component of single-cell RNA-seq (scRNA-seq) processing pipelines. Current approaches to QC implicitly assume that datasets are comprised of one cell type, potentially resulting in biased exclusion of rare cell types. We introduce SampleQC, which robustly...

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Bibliographic Details
Main Authors: Will Macnair, Mark Robinson
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-023-02859-3