Observation of shock-induced protein crystal damage during megahertz serial femtosecond crystallography

Observation of shock-induced protein crystal damage during megahertz serial femtosecond crystallography

Shock waves launched by x-ray pulses in sample-carrying liquid jets may affect protein crystallography data collected at MHz repetition rate x-ray free-electron laser (XFEL) facilities, by damaging the crystals before they are probed. We investigated the shock damage in lysozyme microcrystals using...

Full description

Bibliographic Details
Main Authors: Marie L. Grünbein, Lutz Foucar, Alexander Gorel, Mario Hilpert, Marco Kloos, Karol Nass, Gabriela Nass Kovacs, Christopher M. Roome, Robert L. Shoeman, Miriam Stricker, Sergio Carbajo, William Colocho, Sasha Gilevich, Mark Hunter, Jim Lewandowski, Alberto Lutman, Jason E. Koglin, Thomas J. Lane, Tim van Driel, John Sheppard, Sharon L. Vetter, James L. Turner, R. Bruce Doak, Thomas R. M. Barends, Sébastien Boutet, Andrew L. Aquila, Franz-Josef Decker, Ilme Schlichting, Claudiu A. Stan
Format: Article
Language:English
Published: American Physical Society 2021-01-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.3.013046

Internet

http://doi.org/10.1103/PhysRevResearch.3.013046

Similar Items