S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis

S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis

Summary: Immune-suppressive effects of myeloid-derived suppressor cells (MDSCs) are well characterized during anti-tumor immunity. The complex mechanisms promoting MDSC development and their regulatory effects during autoimmune diseases are less understood. We demonstrate that the endogenous alarmin...

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Bibliographic Details
Main Authors: Meike von Wulffen, Veronika Luehrmann, Stefanie Robeck, Antonella Russo, Lena Fischer-Riepe, Martijn van den Bosch, Peter van Lent, Karin Loser, Dmitry I. Gabrilovich, Sven Hermann, Johannes Roth, Thomas Vogl
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723010173

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http://www.sciencedirect.com/science/article/pii/S2211124723010173

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