CsrA Enhances Cyclic-di-GMP Biosynthesis and <named-content content-type="genus-species">Yersinia pestis</named-content> Biofilm Blockage of the Flea Foregut by Alleviating Hfq-Dependent Repression of the <italic toggle="yes">hmsT</italic> mRNA

CsrA Enhances Cyclic-di-GMP Biosynthesis and <named-content content-type="genus-species">Yersinia pestis</named-content> Biofilm Blockage of the Flea Foregut by Alleviating Hfq-Dependent Repression of the <italic toggle="yes">hmsT</italic> mRNA

ABSTRACT Plague-causing Yersinia pestis is transmitted through regurgitation when it forms a biofilm-mediated blockage in the foregut of its flea vector. This biofilm is composed of an extracellular polysaccharide substance (EPS) produced when cyclic-di-GMP (c-di-GMP) levels are elevated. The Y. pes...

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Bibliographic Details
Main Authors: Amelia R. Silva-Rohwer, Kiara Held, Janelle Sagawa, Nicolas L. Fernandez, Christopher M. Waters, Viveka Vadyvaloo
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mBio
Subjects:
Yersinia pestis
Xenopsylla cheopis fleas
carbon storage regulator
c-di-GMP
Online Access:https://journals.asm.org/doi/10.1128/mBio.01358-21

Internet

https://journals.asm.org/doi/10.1128/mBio.01358-21

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