Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies

Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies

Arginine methylation is a common post-translational modification affecting protein activity and the transcription of target genes when methylation occurs on histone tails. There are nine protein arginine methyltransferases (PRMTs) in mammals, divided into subgroups depending on the methylation they...

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Bibliographic Details
Main Authors: Camille Sauter, John Simonet, Fabien Guidez, Baptiste Dumétier, Baptiste Pernon, Mary Callanan, Jean-Noël Bastie, Romain Aucagne, Laurent Delva
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
hematological malignancies
arginine methylation
PRMT
inhibitors
clinical trials
Online Access:https://www.mdpi.com/2072-6694/14/21/5443

Internet

https://www.mdpi.com/2072-6694/14/21/5443

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