Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid

Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid

L-phenylalanine methyl ester derivative of dexamethasone - derived cortienic acid (DF) was synthesized and its crystal structure was characterized by X-ray diffraction method. The crystal system is orthorhombic with space group P212121 and cell constants a = 8.2969 (3) Å, b = 18.9358 (8) Å,...

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Bibliographic Details
Main Authors: Dobričić Vladimir, Francuski Bojana M., Jaćević Vesna, Rodić Marko V., Vladimirov Sote, Čudina Olivera, Francuski Djordje
Format: Article
Language:English
Published: Serbian Chemical Society 2015-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
17β-carboxamide steroids
X-ray diffraction
biological activity
ear edema test
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391500067D.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391500067D.pdf

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