Effect of Berberine on Bcl-2 Expression in Chronic Lymphocytic Leukemia Compared with Healthy Controls

Effect of Berberine on Bcl-2 Expression in Chronic Lymphocytic Leukemia Compared with Healthy Controls

Background and purpose: Anti-apoptotic protein Bcl-2 prevents apoptosis through the mitochondrial pathway and high-level expression of Bcl-2 is required for survival of chronic lymphocytic leukemia (CLL). Berberine (BBR) is an alkaloid that induces apoptosis of cancer cells via mitochondrial pathway...

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Bibliographic Details
Main Authors: Mehrnoosh Pashaei, Mehdi Barati, Farahnaz Ghahremanfad, Fatemeh Pak, Abolghasem Ajami, Parviz Kokhaei
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2019-03-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
chronic lymphocytic leukemia
bcl-2
berberine
real-time pcr
Online Access:http://jmums.mazums.ac.ir/article-1-12037-en.html

Internet

http://jmums.mazums.ac.ir/article-1-12037-en.html

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