PRKAR1B-AS2 Long Noncoding RNA Promotes Tumorigenesis, Survival, and Chemoresistance via the PI3K/AKT/mTOR Pathway

PRKAR1B-AS2 Long Noncoding RNA Promotes Tumorigenesis, Survival, and Chemoresistance via the PI3K/AKT/mTOR Pathway

Many long noncoding RNAs have been implicated in tumorigenesis and chemoresistance; however, the underlying mechanisms are not well understood. We investigated the role of PRKAR1B-AS2 long noncoding RNA in ovarian cancer (OC) and chemoresistance and identified potential downstream molecular circuitr...

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Bibliographic Details
Main Authors: Abdelrahman M. Elsayed, Emine Bayraktar, Paola Amero, Salama A. Salama, Abdelaziz H. Abdelaziz, Raed S. Ismail, Xinna Zhang, Cristina Ivan, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
lncRNA
PRKAR1B-AS2
AC147651.5
cisplatin resistance
PI3K/AKT/mTOR
ovarian cancer
Online Access:https://www.mdpi.com/1422-0067/22/4/1882

Internet

https://www.mdpi.com/1422-0067/22/4/1882

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