Cystic fibrosis isolates of Pseudomonas aeruginosa retain iron-regulated antimicrobial activity against Staphylococcus aureus through the action of multiple alkylquinolones

Cystic fibrosis (CF) is a hereditary disease that predisposes individuals to pulmonary dysfunction and chronic infections. Early infection of the CF lung with Staphylococcus aureus is common, while Pseudomonas aeruginosa becomes dominant as disease progresses. Emergence of P. aeruginosa likely depen...

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Bibliographic Details
Main Authors: Angela T Nguyen, Jace W Jones, Miguel Camara, Paul Williams, Maureen A Kane, Amanda G Oglesby-Sherrouse
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01171/full