The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis.

The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis.

Mycobacterium tuberculosis (MTb), the causative agent of tuberculosis, can persist in macrophages for decades, maintaining its basic metabolic activities. Phosphoenolpyruvate carboxykinase (Pck; EC 4.1.1.32) is a key player in central carbon metabolism regulation. In replicating MTb, Pck is associat...

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Bibliographic Details
Main Authors: Iva Machová, Martin Hubálek, Martin Lepšík, Lucie Bednárová, Markéta Pazderková, Vladimír Kopecký, Jan Snášel, Jiří Dostál, Iva Pichová
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5279734?pdf=render

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http://europepmc.org/articles/PMC5279734?pdf=render

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