Inhibition of Endoplasmic Reticulum Stress Improves Acetylcholine-Mediated Relaxation in the Aorta of Type-2 Diabetic Rats

Inhibition of Endoplasmic Reticulum Stress Improves Acetylcholine-Mediated Relaxation in the Aorta of Type-2 Diabetic Rats

Endoplasmic reticulum (ER) stress contributes to insulin resistance and macro- and microvascular complications associated with diabetes. This study aimed to evaluate the effect of ER stress inhibition on endothelial function in the aorta of type-2 diabetic rats. Type-2 diabetes was developed in male...

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Bibliographic Details
Main Authors: Sagir Mustapha, Ahmad Khusairi Azemi, Wan Amir Nizam Wan Ahmad, Aida Hanum Ghulam Rasool, Mohd Rais Mustafa, Siti Safiah Mokhtar
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
endothelial function
ER stress
tauro-ursodeoxycholic acid (TUDCA)
type-2 diabetes
vasculopathy
Online Access:https://www.mdpi.com/1420-3049/27/16/5107

Internet

https://www.mdpi.com/1420-3049/27/16/5107

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