Production of Proliferation- and Differentiation-Competent Porcine Myoblasts for Preclinical Studies in a Porcine Large Animal Model of Muscular Insufficiency

Production of Proliferation- and Differentiation-Competent Porcine Myoblasts for Preclinical Studies in a Porcine Large Animal Model of Muscular Insufficiency

Muscular insufficiency is observed in many conditions after injury, chronic inflammation, and especially in elderly populations. Causative cell therapies for muscle deficiencies are not state of the art. Animal models to study the therapy efficacy are, therefore, needed. We developed an improved pro...

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Bibliographic Details
Main Authors: Jasmin Knoll, Bastian Amend, Tanja Abruzzese, Niklas Harland, Arnulf Stenzl, Wilhelm K. Aicher
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Life
Subjects:
cell-based muscle regeneration
large animal model of cell therapy
porcine myoblast
myogenic differentiation
myotubes
Online Access:https://www.mdpi.com/2075-1729/14/2/212

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https://www.mdpi.com/2075-1729/14/2/212

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