Targeting β-cell dedifferentiation and transdifferentiation: opportunities and challenges

The most distinctive pathological characteristics of diabetes mellitus induced by various stressors or immune-mediated injuries are reductions of pancreatic islet β-cell populations and activity. Existing treatment strategies cannot slow disease progression; consequently, research to genetically eng...

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Bibliographic Details
Main Authors: Wenrui Wang, Chuan Zhang
Format: Article
Language:English
Published: Bioscientifica 2021-08-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/10/8/EC-21-0260.xml