Inflammasome-IL-1β signaling mediates ethanol inhibition of hippocampal neurogenesis

AbstractRegulation of hippocampal neurogenesis is poorly understood, but appears to contribute to mood and cognition. Ethanol and neuroinflammation are known to reduce neurogenesis. We have found that ethanol induces neuroinflammation supporting the hypothesis that ethanol induction of neuroinflam...

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Bibliographic Details
Main Author: Fulton eCrews
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00077/full