Charge and Size Dual Switchable Nanocage for Novel Triple‐Interlocked Combination Therapy Pattern

Charge and Size Dual Switchable Nanocage for Novel Triple‐Interlocked Combination Therapy Pattern

Abstract Combination therapy is a current hot topic in cancer treatment. Multiple synergistic effects elicited by combined drugs are essential in improving antitumor activity. Herein, a pH‐triggered charge and size dual switchable nanocage co‐loaded with abemaciclib and IMD‐0354 (PA/PI‐ND) is report...

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Bibliographic Details
Main Authors: Rui Yang, Zipeng Zhang, Shunli Fu, Teng Hou, Weiwei Mu, Shuang Liang, Tong Gao, Li Guan, Yuxiao Fang, Yongjun Liu, Na Zhang
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Advanced Science
Subjects:
dual switchable nanocages
deep tumor penetration
pH‐triggered release
triple‐interlocked combination therapy
tumor‐associated macrophage repolarization
Online Access:https://doi.org/10.1002/advs.202000906

Internet

https://doi.org/10.1002/advs.202000906

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