Cytoskeletal Protein Zyxin Inhibits the Activity of Genes Responsible for Embryonic Stem Cell Status

Cytoskeletal Protein Zyxin Inhibits the Activity of Genes Responsible for Embryonic Stem Cell Status

Summary: Zyxin is a cytoskeletal LIM-domain protein that regulates actin cytoskeleton assembly and gene expression. In the present work, we find that zyxin downregulation in Xenopus laevis embryos reduces the expression of numerous genes that regulate cell differentiation, but it enhances that of se...

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Bibliographic Details
Main Authors: Elena A. Parshina, Fedor M. Eroshkin, Eugeny E. Оrlov, Fatima K. Gyoeva, Arina G. Shokhina, Dmitry B. Staroverov, Vsevolod V. Belousov, Nadezhda A. Zhigalova, Egor B. Prokhortchouk, Andrey G. Zaraisky, Natalia Y. Martynova
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Cell Reports
Subjects:
Zyxin
Ybx1
actin cytoskeleton regulation
genes responsible for stem cells status
pou5f3
Nanog
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720313851

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http://www.sciencedirect.com/science/article/pii/S2211124720313851

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