Ligand-based modelling for screening natural compounds targeting Minichromosome Maintenance Complex Component-7 for potential anticancer effects

Ligand-based modelling for screening natural compounds targeting Minichromosome Maintenance Complex Component-7 for potential anticancer effects

Minichromosome Maintenance Complex Component-7 (MCM7) plays a significant role in DNA replication. A comprehensive search of oncogenic databases (UALCAN and KMplot) revealed overexpression or upregulation of MCM7 in a number of cancers (including top prevalent cancer types worldwide). Thus, identifi...

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Bibliographic Details
Main Authors: Md Nazmus Samdani, Rumman Reza, Niaz Morshed, Muhammad Asaduzzaman, Abul Bashar Mir Md Khademul Islam
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Informatics in Medicine Unlocked
Subjects:
MCM7
Anti-cancer
Virtual screening
Molecular dynamics
Molecular docking
Pharmacophore
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914822002891

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http://www.sciencedirect.com/science/article/pii/S2352914822002891

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