Antibiotics Significantly Decrease the Survival of Head and Neck Carcinoma Patients with Immunotherapy: A Real-World Analysis of More Than 3000 Cases

Antibiotics Significantly Decrease the Survival of Head and Neck Carcinoma Patients with Immunotherapy: A Real-World Analysis of More Than 3000 Cases

Objective: The human gut microbiome is strongly influenced by the administration of drugs, namely antibiotics. We hypothesized that the effectiveness of immunotherapy with pembrolizumab in oral squamous cell carcinoma patients is decreased by the administration of antibiotics three months before and...

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Bibliographic Details
Main Authors: Saskia Preissner, Max Heiland, Robert Preissner, Markus Wirth, Barbara Wollenberg
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
oral squamous cell carcinoma
oral cancer
immunotherapy
pembrolizumab
antibiotics
gut microbiome
Online Access:https://www.mdpi.com/2072-6694/15/8/2342

Internet

https://www.mdpi.com/2072-6694/15/8/2342

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