Neuronal activity-dependent ATP enhances the pro-growth effect of repair Schwann cell extracellular vesicles by increasing their miRNA-21 loading

Neuronal activity-dependent ATP enhances the pro-growth effect of repair Schwann cell extracellular vesicles by increasing their miRNA-21 loading

Functional recovery after peripheral nerve injuries is critically dependent on axonal regeneration. Several autonomous and non-cell autonomous processes regulate axonal regeneration, including the activation of a growth-associated transcriptional program in neurons and the reprogramming of different...

Full description

Bibliographic Details
Main Authors: Cristian Saquel, Romina J. Catalan, Rodrigo Lopez-Leal, Ramon A. Ramirez, David Necuñir, Ursula Wyneken, Christophe Lamaze, Felipe A. Court
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Schwann cell
extracellular vesicles
ATP
purinergic receptors
axonal growth
axonal regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.943506/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2022.943506/full

Similar Items