Characterizing the relationship between steady state and response using analytical expressions for the steady states of mass action models.

The steady states of cells affect their response to perturbation. Indeed, diagnostic markers for predicting the response to therapeutic perturbation are often based on steady state measurements. In spite of this, no method exists to systematically characterize the relationship between steady state a...

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Bibliographic Details
Main Authors: Paul Michael Loriaux, Glenn Tesler, Alexander Hoffmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23509437/pdf/?tool=EBI