Development of an antibody fused with an antimicrobial peptide targeting Pseudomonas aeruginosa: A new approach to prevent and treat bacterial infections.

Development of an antibody fused with an antimicrobial peptide targeting Pseudomonas aeruginosa: A new approach to prevent and treat bacterial infections.

The increase in emerging drug resistant Gram-negative bacterial infections is a global concern. In addition, there is growing recognition that compromising the microbiota through the use of broad-spectrum antibiotics can impact long term patient outcomes. Therefore, there is the need to develop new...

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Bibliographic Details
Main Authors: Kenneth Johnson, James C Delaney, Thomas Guillard, Fany Reffuveille, Jennifer Varin-Simon, Kai Li, Andrew Wollacott, Eric Frapy, Surin Mong, Hamid Tissire, Karthik Viswanathan, Faycal Touti, Gregory J Babcock, Zachary Shriver, Bradley L Pentelute, Obadiah Plante, David Skurnik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011612

Internet

https://doi.org/10.1371/journal.ppat.1011612

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