Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson’s disease carrying a novel heterozygotic PARK8 (LRRK2) mutation

Leucine-rich repeat kinase 2 (LRRK2), also known as Dardarin (derived from the Basque word “dardara,” meaning tremor), is a protein kinase encoded by the PARK8 gene. This protein is mainly distributed in the cytoplasm; however, it is also present in the mitochondrial outer membrane. Mutations in the...

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Bibliographic Details
Main Authors: Lingfei Li, Xiaoli Si, Jiayin Yang, Meng Lei, Huifang Liu, Jie Ruan, Hanting Fu, Wenxuan Li, Hui Yang, Xiaoguang Lei, Hongfei Sang
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122003440