Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies
Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various urological diseases. However, the urinary Tamm-Horsfall protein (THP) complex, which forms at reduced temperatures, may affect EV isolation and may...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
AboutScience Srl
2016-03-01
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Series: | Journal of Circulating Biomarkers |
Online Access: | https://doi.org/10.5772/62579 |