Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies

Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies

Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various urological diseases. However, the urinary Tamm-Horsfall protein (THP) complex, which forms at reduced temperatures, may affect EV isolation and may...

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Bibliographic Details
Main Authors:	Magda Wachalska, Danijela Koppers-Lalic, Monique van Eijndhoven, Michiel Pegtel, Albert A. Geldof, Andrea D. Lipinska, R. Jeroen van Moorselaar, Irene V. Bijnsdorp
Format:	Article
Language:	English
Published:	AboutScience Srl 2016-03-01
Series:	Journal of Circulating Biomarkers
Online Access:	https://doi.org/10.5772/62579

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