Evaluation of therapeutic efficacy of 211At-labeled farletuzumab in an intraperitoneal mouse model of disseminated ovarian cancer

Introduction: Antibodies labeled with alpha-emitter astatine-211 have previously shown effective in intraperitoneal (i.p.) treatments of ovarian cancer. In the present work we explore the use of investigational farletuzumab, aimed at the folate receptor alpha. The aim was to evaluate the biodistribu...

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Bibliographic Details
Main Authors: Stig Palm, Tom Bäck, Emma Aneheim, Andreas Hallqvist, Ragnar Hultborn, Lars Jacobsson, Holger Jensen, Sture Lindegren, Per Albertsson
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332030365X