Protein tyrosine phosphatase 1 protects human pancreatic cancer from erastin-induced ferroptosis

Background: Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignancy due to the lack of early detection method, therapeutic drug and target. We noticed that the expression of Protein Tyrosine Phosphatase Mitochondria1(PTPMT1) is upregulated in PDAC. However, its role in pancreatic cancer remain...

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Bibliographic Details
Main Authors: Xiao-Dong Huang, PhD, Feng-Jun Xiao, PhD, Yu-Tong Guo, Yang Sun, Yi-Kun Zhang, PhD, Xian-Jie Shi, PhD
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Asian Journal of Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1015958421007892