Syndecan-1 (CD138) immunohistochemical expression patterns in lupus nephritis; reflections on different clinicopathological parameters

Introduction: Syndecan 1 (SCD1) is a lectin expressed at the surface of renal tubular epithelial cells and plasma cells. In epithelial cells, cell surface syndecan1 is cleaved by inflammation-induced proteases (eg, ADAMTS, MMP), since loss of cell surface syndecan1 is associated with higher suscepti...

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Bibliographic Details
Main Authors: Marwa M Shakweer, Lobna S Shash
Format: Article
Language:English
Published: Society of Diabetic Nephropathy Prevention 2021-01-01
Series:Journal of Nephropathology
Subjects:
Online Access:https://nephropathol.com/PDF/jnp-10-e06.pdf