Challenges for the Development of Extracellular Vesicle-Based Nucleic Acid Medicines

Nucleic acid drugs, such as siRNAs, antisense oligonucleotides, and miRNAs, exert their therapeutic effects by causing genetic changes in cells. However, there are various limitations in their delivery to target organs and cells, making their application to cancer treatment difficult. Extracellular...

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Bibliographic Details
Main Authors: Naoya Kuriyama, Yusuke Yoshioka, Shinsuke Kikuchi, Akihiko Okamura, Nobuyoshi Azuma, Takahiro Ochiya
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/23/6137