Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer

Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer

MMP10, which is upregulated in 86% of primary tongue tumors with lymph node metastases, is negatively regulated by miR-944 and promotes nodal metastasis in an orthotopic tongue cancer mouse model through the AXL signaling pathway.

Bibliographic Details
Main Authors: Bhasker Dharavath, Ashwin Butle, Ankita Pal, Sanket Desai, Pawan Upadhyay, Aishwarya Rane, Risha Khandelwal, Sujith Manavalan, Rahul Thorat, Kavita Sonawane, Richa Vaish, Poonam Gera, Munita Bal, Anil K. D’Cruz, Sudhir Nair, Amit Dutt
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04437-6

Internet

https://doi.org/10.1038/s42003-023-04437-6

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