Activating FcγR function depends on endosomal-signaling platforms

Activating FcγR function depends on endosomal-signaling platforms

Summary: Cell surface receptor internalization can either terminate signaling or activate alternative endosomal signaling pathways. We investigated here whether endosomal signaling is involved in the function of the human receptors for Fc immunoglobulin fragments (FcRs): FcαRI, FcγRIIA, and FcγRI. A...

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Bibliographic Details
Main Authors: Samira Benadda, Mathilde Nugue, Despoina Koumantou, Marcelle Bens, Mariacristina De Luca, Olivier Pellé, Renato C. Monteiro, Irini Evnouchidou, Loredana Saveanu
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Biological sciences
Immunology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301132X

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http://www.sciencedirect.com/science/article/pii/S258900422301132X

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