The POU-HD TFs impede the replication efficiency of several human papillomavirus genomes

Abstract Human papillomavirus (HPV) is a double-stranded DNA virus that infects cutaneous and mucosal epithelial cells. HPV replication initiates at the origin (ori), located within a noncoding region near the major early promoter. Only two viral proteins, E1 and E2, are essential for replication, w...

Full description

Bibliographic Details
Main Authors: Martin Kala, Sofiya Babok, Nika Mikhailava, Marko Piirsoo, Alla Piirsoo
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-024-02334-w