YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis

YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis

Th17 cells are involved in rheumatoid arthritis (RA) pathogenesis. Our previous studies have revealed that transcription factor Yin Yang 1 (YY1) plays an important role in the pathogenic mechanisms of RA. However, whether YY1 has any role in Th17 cell pathogenicity and what molecular regulatory mech...

Full description

Bibliographic Details
Main Authors: Jinpiao Lin, Jifeng Tang, Junyu Lin, Yujue He, Ziqing Yu, Renquan Jiang, Bin Yang, Qishui Ou
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-11-01
Series:JCI Insight
Subjects:
Autoimmunity
Immunology
Online Access:https://doi.org/10.1172/jci.insight.149985

Internet

https://doi.org/10.1172/jci.insight.149985

Similar Items