The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression

The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression

Human cytomegalovirus (HCMV) infection can lead to either lytic or latent infection, which is dependent on the regulation of the viral major immediate early promoter (MIEP). Suppression of the MIEP is a pre-requisite for latency and is driven by repressive epigenetic modifications at the MIEP during...

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Bibliographic Details
Main Authors: Emma Poole, Jonathan Lau, Ian Groves, Kate Roche, Eain Murphy, Maria Carlan da Silva, Matthew Reeves, John Sinclair
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Viruses
Subjects:
human cytomegalovirus
latency
chromatin
Online Access:https://www.mdpi.com/1999-4915/15/9/1875

Internet

https://www.mdpi.com/1999-4915/15/9/1875

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