Transcriptome signatures preceding the induction of anti-stalk antibodies elicited after universal influenza vaccination

Transcriptome signatures preceding the induction of anti-stalk antibodies elicited after universal influenza vaccination

Abstract A phase 1 clinical trial to test the immunogenicity of a chimeric group 1 HA (cHA) universal influenza virus vaccine targeting the conserved stalk domain of the hemagglutinin of influenza viruses was carried out. Vaccination with adjuvanted-inactivated vaccines induced high anti-stalk antib...

Full description

Bibliographic Details
Main Authors: Teresa Aydillo, Ana S. Gonzalez-Reiche, Daniel Stadlbauer, Mary Anne Amper, Venugopalan D. Nair, Chiara Mariottini, Stuart C. Sealfon, Harm van Bakel, Peter Palese, Florian Krammer, Adolfo García-Sastre
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00583-w

Internet

https://doi.org/10.1038/s41541-022-00583-w

Similar Items