Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by <i>Caenorhabditis elegans</i> NMAD-1A

Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by <i>Caenorhabditis elegans</i> NMAD-1A

<i>N</i><sup>6</sup>-methyladenine (6mA) of DNA is an emerging epigenetic mark in the genomes of <i>Chlamydomonas</i>, <i>Caenorhabditis elegans</i>, and mammals recently. Levels of 6mA undergo drastic fluctuation and thus affect fertility during meios...

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Bibliographic Details
Main Authors: Guohui Shang, Meiting Yang, Min Li, Lulu Ma, Yunlong Liu, Jun Ma, Yiyun Chen, Xue Wang, Shilong Fan, Mengjia Xie, Wei Wu, Shaodong Dai, Zhongzhou Chen
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
NMAD-1A
6mA demethylation
AlkB homolog
crystal structure
Flips
CTD
Online Access:https://www.mdpi.com/1422-0067/25/2/686

Internet

https://www.mdpi.com/1422-0067/25/2/686

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