The synovial fluid fibroblast-like synoviocyte: A long-neglected piece in the puzzle of rheumatoid arthritis pathogenesis

Rheumatoid arthritis (RA) is a systemic autoimmune disease during which fibroblast-like synoviocytes (FLS) contribute to both joint inflammation and destruction. FLS represent the core component of the synovial membrane. Following inflammation of this membrane, an effusion of cell-rich synovial flui...

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Bibliographic Details
Main Authors: Dorra Elhaj Mahmoud, Wajih Kaabachi, Nadia Sassi, Lamjed Tarhouni, Sonia Rekik, Samia Jemmali, Hela Sehli, Maryam Kallel-Sellami, Elhem Cheour, Lilia Laadhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.942417/full