Cardiac Alternans Occurs through the Synergy of Voltage- and Calcium-Dependent Mechanisms

Cardiac alternans is characterized by alternating weak and strong beats of the heart. This signaling at the cellular level may appear as alternating long and short action potentials (APs) that occur in synchrony with alternating large and small calcium transients, respectively. Previous studies have...

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Bibliographic Details
Main Authors: Minh Tuan Hoang-Trong, Aman Ullah, William Jonathan Lederer, Mohsin Saleet Jafri
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/10/794