N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression

Abstract The study was design to investigate the functional roles of Wilms tumor 1-associated protein (WTAP), an enzyme catalyzes m6A modification, in the pathogenesis of osteoarthritis (OA) and further elucidate its possible regulatory mechanism. Herein, we discovered that WTAP was outstandingly up...

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Bibliographic Details
Main Authors: Zhaowei Lin, Tao Jiang, Wei Zheng, Jiayuan Zhang, Anan Li, Chao Lu, Wengang Liu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell Communication and Signaling
Online Access:https://doi.org/10.1186/s12964-023-01228-8