Airways tissue expression of type I interferons and their stimulated genes is higher in children than adults

Airways tissue expression of type I interferons and their stimulated genes is higher in children than adults

There is emerging evidence that age-dependent differences in susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) correlate with stronger innate immune response in the upper respiratory tract in children compared to adults. The efficient induction of interferon (IFN) alpha...

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Bibliographic Details
Main Authors: Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Shirin Hafezi, Zaina Kalaji, Mohamed Temsah, Saleh Almuhsen, Habiba S. Alsafar, Qutayba Hamid, Rabih Halwani
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
SARS-CoV-2
IFN alpha
IFN beta
Type I interferon
Interferon-stimulated genes (ISGs)
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022030122

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022030122

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