Comparative analysis of DNA extraction and PCR product purification methods for cervicovaginal microbiome analysis using cpn60 microbial profiling.

<h4>Background</h4>The microbiota of the lower female genital tract plays an important role in women's health. Microbial profiling using the chaperonin60 (cpn60) universal target (UT) improves resolution of vaginal species associated with negative health outcomes compared to the mor...

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Bibliographic Details
Main Authors: Elinor Shvartsman, Meika E I Richmond, John J Schellenberg, Alana Lamont, Catia Perciani, Justen N H Russell, Vanessa Poliquin, Adam Burgener, Walter Jaoko, Paul Sandstrom, Kelly S MacDonald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0262355