Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage.

Irradiation and DNA-damaging chemotherapeutic agents are commonly used in anticancer treatments. Following DNA damage FOXM1 protein levels are often elevated. In this study, we sought to investigate the potential role of FOXM1 in programmed cell death induced by DNA-damage. Human cancer cells after...

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Bibliographic Details
Main Authors: Marianna Halasi, Andrei L Gartel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290538?pdf=render