Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage.
Irradiation and DNA-damaging chemotherapeutic agents are commonly used in anticancer treatments. Following DNA damage FOXM1 protein levels are often elevated. In this study, we sought to investigate the potential role of FOXM1 in programmed cell death induced by DNA-damage. Human cancer cells after...
Κύριοι συγγραφείς: | Marianna Halasi, Andrei L Gartel |
---|---|
Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Public Library of Science (PLoS)
2012-01-01
|
Σειρά: | PLoS ONE |
Διαθέσιμο Online: | http://europepmc.org/articles/PMC3290538?pdf=render |
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.
ανά: Uppoor G Bhat, κ.ά.
Έκδοση: (2009-01-01) -
FoxM1 is a general target for proteasome inhibitors.
ανά: Uppoor G Bhat, κ.ά.
Έκδοση: (2009-08-01) -
Novel FOXM1 inhibitor identified via gene network analysis induces autophagic FOXM1 degradation to overcome chemoresistance of human cancer cells
ανά: Mikhail S. Chesnokov, κ.ά.
Έκδοση: (2021-07-01) -
FOXM1-AKT Positive Regulation Loop Provides Venetoclax Resistance in AML
ανά: Mikhail S Chesnokov, κ.ά.
Έκδοση: (2021-07-01) -
Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors
ανά: Andrei L. Gartel
Έκδοση: (2014-01-01)