Lebetin 2, a Snake Venom-Derived B-Type Natriuretic Peptide, Provides Immediate and Prolonged Protection against Myocardial Ischemia-Reperfusion Injury via Modulation of Post-Ischemic Inflammatory Response

Lebetin 2, a Snake Venom-Derived B-Type Natriuretic Peptide, Provides Immediate and Prolonged Protection against Myocardial Ischemia-Reperfusion Injury via Modulation of Post-Ischemic Inflammatory Response

Myocardial infarction (MI) followed by left ventricular (LV) remodeling is the most frequent cause of heart failure. Lebetin 2 (L2), a snake venom-derived natriuretic peptide, exerts cardioprotection during acute myocardial ischemia-reperfusion (IR) ex vivo. However, its effects on delayed consequen...

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Bibliographic Details
Main Authors: Bochra Tourki, Anais Dumesnil, Elise Belaidi, Slim Ghrir, Diane Godin-Ribuot, Naziha Marrakchi, Vincent Richard, Paul Mulder, Erij Messadi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Toxins
Subjects:
natriuretic peptide
myocardial infarction
ischemia-reperfusion injury
inflammation
fibrosis
Online Access:https://www.mdpi.com/2072-6651/11/9/524

Internet

https://www.mdpi.com/2072-6651/11/9/524

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