Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition
Abstract LINE-1 (L1) elements are a class of transposons, comprising approximately 19% and 21% of the mouse and human genomes, respectively. L1 retrotransposons can reverse transcribe their own RNA sequence into a de novo DNA copy integrated into a new genomic location. This activity, known as retro...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Genética
2023-01-01
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| Series: | Genetics and Molecular Biology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572023000100701&lng=en&tlng=en |