Interchromosomal translocation in neural progenitor cells exposed to L1 retrotransposition
Abstract LINE-1 (L1) elements are a class of transposons, comprising approximately 19% and 21% of the mouse and human genomes, respectively. L1 retrotransposons can reverse transcribe their own RNA sequence into a de novo DNA copy integrated into a new genomic location. This activity, known as retro...
Main Author: | Alysson R. Muotri |
---|---|
Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Genética
2023-01-01
|
Series: | Genetics and Molecular Biology |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572023000100701&lng=en&tlng=en |
Similar Items
-
HCV Activates Somatic L1 Retrotransposition—A Potential Hepatocarcinogenesis Pathway
by: Praveen D. Sudhindar, et al.
Published: (2021-10-01) -
An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson’s Disease Risk and Progression in the PPMI Cohort
by: Abigail L. Pfaff, et al.
Published: (2020-09-01) -
APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition
by: Sandra R Richardson, et al.
Published: (2014-04-01) -
L1 retrotransposition in the soma: a field jumping ahead
by: Geoffrey J. Faulkner, et al.
Published: (2018-07-01) -
A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition
by: Anastasia Barkova, et al.
Published: (2022-11-01)