Innate activation of human neutrophils and neutrophil-like cells by the pro-inflammatory bacterial metabolite ADP-heptose and Helicobacter pylori

Innate activation of human neutrophils and neutrophil-like cells by the pro-inflammatory bacterial metabolite ADP-heptose and Helicobacter pylori

Lipopolysaccharide inner core heptose metabolites, including ADP-heptose, play a substantial role in the activation of cell-autonomous innate immune responses in eukaryotic cells, via the ALPK1-TIFA signaling pathway, as demonstrated for various pathogenic bacteria. The important role of LPS heptose...

Full description

Bibliographic Details
Main Authors: Larissa Faass, Martina Hauke, Saskia C. Stein, Christine Josenhans
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:International Journal of Medical Microbiology
Subjects:
Bacterial heptose metabolites
Neutrophils
Innate immune activation
Helicobacter pylori
Inflammation
Chronic infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1438422123000139

Internet

http://www.sciencedirect.com/science/article/pii/S1438422123000139

Similar Items