Differences in Cholesterol Metabolism, Hepato-Intestinal Aging, and Hepatic Endocrine Milieu in Rats as Affected by the Sex and Age

Differences in Cholesterol Metabolism, Hepato-Intestinal Aging, and Hepatic Endocrine Milieu in Rats as Affected by the Sex and Age

Age and sex influence serum cholesterol levels, but the underlying mechanisms remain unclear. To investigate further, we measured cholesterol, precursors (surrogate synthesis markers), degradation products (oxysterols and bile acid precursors) in serum, the liver, jejunum, and ileum, as well as seru...

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Bibliographic Details
Main Authors: Branka Šošić-Jurjević, Dieter Lütjohann, Svetlana Trifunović, Slađan Pavlović, Slavica Borković Mitić, Ljubiša Jovanović, Nataša Ristić, Ljiljana Marina, Vladimir Ajdžanović, Branko Filipović
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
sex differences
age
cholesterol metabolism
oxidative stress
liver
small intestine
Online Access:https://www.mdpi.com/1422-0067/24/16/12624

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https://www.mdpi.com/1422-0067/24/16/12624

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